Vibrotactile Whisker Frequency Discrimination in Head-Fixed Mice
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چکیده
A Novel Two-alternative Forced Choice Paradigm for Bilateral 3 Vibrotactile Whisker Frequency Discrimination in Head-Fixed Mice 4 and Rats 5 Johannes M. Mayrhofer, Vida Skreb, Wolfger von der Behrens, Simon Musall, Bruno Weber and 6 Florent Haiss* 7 8 Institute of Pharmacology and Toxicology, University of Zürich, Zürich, Switzerland 9 10 Running title: bilateral frequency discrimination in head fixed rodents 11 With 22 text pages, 7 figures 12 * Correspondence: Florent Haiss 13 Institute of Pharmacology & Toxicology 14 University of Zürich 15 Rämistrasse 100 16 8091 Zürich 17 Switzerland 18 Phone: +41 442553632 19 Fax: +41 442554428 20 email: [email protected] 21 22 These authors contributed equally to this work. 23 24 25 Articles in PresS. J Neurophysiol (October 10, 2012). doi:10.1152/jn.00488.2012
منابع مشابه
Novel two-alternative forced choice paradigm for bilateral vibrotactile whisker frequency discrimination in head-fixed mice and rats.
Rats and mice receive a constant bilateral stream of tactile information with their large mystacial vibrissae when navigating in their environment. In a two-alternative forced choice paradigm (2-AFC), head-fixed rats and mice learned to discriminate vibrotactile frequencies applied simultaneously to individual whiskers on the left and right sides of the snout. Mice and rats discriminated 90-Hz ...
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Rats explore environments by sweeping their whiskers across objects and surfaces. Both sensor movement and repetitive sweeping typical for this behavior require that vibrotactile signals are integrated over time. While temporal integration properties of neurons along the whisker somatosensory pathway have been studied extensively, the consequences for behavior are unknown. Here, we investigate ...
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تاریخ انتشار 2012